Ezmek, BahadırPişkin, BülentSipahi, Cumhur2022-03-182022-03-182021EZMEK B,PİŞKİN B,SİPAHİ O. C (2021). Therapeutic efficiency analyses of mandibular advancement devices using polysomnography, smartphone sleep applications, and simple pulse oximetry. Gülhane Tıp Dergisi, 63(1), 52 - 58. Doi: 10.4274/gulhane.galenos.2020.11791302-04712146-8052https://doi.org/10.4274/gulhane.galenos.2020.1179https://hdl.handle.net/20.500.12695/1534TARAMATRDİZİNTARAMASCOPUSAims: Oral appliances are non-invasive solutions for obstructive sleep apnea (OSA). The aim of the present study was to determine the therapeutic efficiency of mandibular advancement devices (MAD), using polysomnography (PSG), smartphone sleep applications (SSA), and simple pulse oximetry (SPO) for OSA patients. Methods: Totally 18 mild-moderate OSA patients (8 females and 10 males, aged between 34 and 83 years) with subjective snoring complaints were selected. The diagnostic PSG tests were accepted as initial PSG. Each patient was subjected to SPO and SSA at 3 different nights at home. The mean diagnostic values of oxygen desaturation index (ODI), snoring intensity score (SIS) and snoring percentage (SP) were obtained. Non-titratable-customized MADs (NTC-MAD) with 60-75% of maximal mandibular protrusion were fabricated. SPO and SSA measurements were repeated at the 1st, 4th, 12th, and 24th weeks of the treatment process. At the 24th week of the treatment, the PSG tests were repeated and all PSG, SPO, and SSA values were compared with initial diagnostic values. Results: There was no significant difference in body mass index and neck circumference values during the treatment (p>0.05). The success rate of NTC-MAD treatment was about 68.7% according to the success criterion of MAD treatment as the decrease of apnea-hypopnea index below 5 per hour. ODI, SIS, and SP values showed a significant decrease during the treatment (p<0.01). A maximum decrease in SPO and SSA data were obtained at the 12th week of NTCMAD use (p<0.05). Conclusions: NTC-MADs significantly decreased snoring intensity and frequency and may be accepted as effective devices in the treatment of OSA.eninfo:eu-repo/semantics/openAccessSnoringobstructive sleep apneamandibular advancement devicepulse oximeter devicesmartphone sleep applicationsArticle6315258Q3