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Histological evaluation of the effects of rapamycin and 3-methyladenine on cisplatin-induced epididymal injury in rats
(Cukurova Medical Journal, 2021)
Purpose: In this study, we aimed to determine the effects of autophagy inhibitor and activator on Cisplatin (Cis)-induced tissue damage.
Materials and Methods: A total of 24 male Wistar albino rats were divided into 4 ...
Kronik Hipoksiye Maruz Bırakılan Ratlardaki Mide Ghrelin Miktarı Üzerine Klorokuin’in Etkisi
(2019)
Giriş Amaç Yüksek irtifada yaşanan komplikasyonlardan biri olan Anoreksiya, çevresel
durumu sinyallerde enerji durumunu belirleyen ve iştahı kontrol eden hipoksinin neden olduğu
rahatsızlıklardan kaynaklanmaktadır. ...
The Dose-Dependent Effects Of Doxorubicin In Ratliver Tissue
(1st International Ahi Evran Medical and Health Science Congress (IAMHC), 2019)
Introduction: Doxorubicin (DOX) is an anthracycline antibiotic used as an anticancer agent and is a widely
used chemotherapeutic for many cancer types such as sarcoma, acute lymphoblastic leukaemia and as well as
breast ...
Effect of Chloroquine in Chronic Hypoxia-Induced Bowel Damage
(20. Ulusal Anatomi Kongresi, 2019)
Effect of chloroquine in chronic hypoxia-induced bowel damage
Evaluation Of Epididymitis Tissue Of Cisplatin-Induced Rats
(SANAR, 2020)
As a chemotherapeutic agent, cisplatin is an antineoplastic agent used in the treatment of
various solid tumors such as lung, testicle and bladder cancer (Ezaki, Nishiumi, Azuma, &
Yoshida, 2017; Salem, Helmi, & Assaf, ...
Klorokuin endoplazmik retikulum stresini ve enflamasyonu inhibe ederek sıçanlarda adriamisin uyarılı kardiyotoksisiteyi engeller
(Türk Hijyen ve Deneysel Biyoloji Dergisi, 2020)
Amaç: Adriamisin (ADR) kanser türlerinde kullanılan kemoterapötik bir ilaç olarak bilinmektedir. ADR uyarılı kardiyomiyopati toksik özelliğinden dolayı ilacın kullanımını zorlaştırmaktadır. ADR uyarılı kardiyotoksisitede ...
Investigation of the Effect of Chloroquine on Adriamcycin-Induced Kidney Damage
(2022)
Although Adriamycin (ADR) is an important anticancer drug used in chemotherapy, it causes nephrotoxicity. The inflammation pathway has an important role in ADR-induced nephrotoxicity. Chloroquine (CLQ), which is used as ...
Protective effect of melatonin on cisplatin-induced liver injury in rats
(Cukurova Medical Journal, 2022)
Purpose: We aimed to evaluate the protective effect of melatonin (Mel) on experimental hepatatoxicity induced by cisplatin (Cis).
Materials and Methods: A total of 40 Wistar Albino rats were used. Control group (n = 10) ...
Chloroquine attenuates chronic hypoxia-induced testicular damage via suppressing endoplasmic reticulum stress and apoptosis in experimental rat model
(Wiley Online Library, 2022)
Chronic hypoxia negatively affects male fertility by causing pathological changes in male reproductive system. However, underlying mechanisms of this damage are unknown. Chloroquine (CLQ) is an anti-inflammatory agent that ...
Mitigative effects of chloroquine treatment against hypoxia-induced intestinal injury: a histological and immunohistochemical study
(Türk Hijyen ve Deneysel Biyoloji Dergisi, 2022)
Objective: Hypoxia has an important role in the disruption of intestinal mucosal integrity because of
inflammation and apoptosis induced by inflammatory cytokines such as TNF-α (Tumor necrosis factor-alpha), IL-6 and ...
