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The Dose-Dependent Effects Of Doxorubicin In Ratliver Tissue
(1st International Ahi Evran Medical and Health Science Congress (IAMHC), 2019)
Introduction: Doxorubicin (DOX) is an anthracycline antibiotic used as an anticancer agent and is a widely
used chemotherapeutic for many cancer types such as sarcoma, acute lymphoblastic leukaemia and as well as
breast ...
Effect of Chloroquine in Chronic Hypoxia-Induced Bowel Damage
(20. Ulusal Anatomi Kongresi, 2019)
Effect of chloroquine in chronic hypoxia-induced bowel damage
Researches on the protective effect of caffeic acid phenethyl ester on testicular 2 damage caused by cisplatin
(2020)
BACKGROUND/AIM:Cisplatin (CP), a chemotherapeutic drug, causes damage to spermatogenic serial cells, Sertoli cells and Leydig cells in rat testicles. We aimed to investigate the protective effect of caffeic acid phenethyl ...
Evaluation Of Epididymitis Tissue Of Cisplatin-Induced Rats
(SANAR, 2020)
As a chemotherapeutic agent, cisplatin is an antineoplastic agent used in the treatment of
various solid tumors such as lung, testicle and bladder cancer (Ezaki, Nishiumi, Azuma, &
Yoshida, 2017; Salem, Helmi, & Assaf, ...
Investigation of the Effect of Chloroquine on Adriamcycin-Induced Kidney Damage
(2022)
Although Adriamycin (ADR) is an important anticancer drug used in chemotherapy, it causes nephrotoxicity. The inflammation pathway has an important role in ADR-induced nephrotoxicity. Chloroquine (CLQ), which is used as ...
Mitigative effects of chloroquine treatment against hypoxia-induced intestinal injury: a histological and immunohistochemical study
(Türk Hijyen ve Deneysel Biyoloji Dergisi, 2022)
Objective: Hypoxia has an important role in the disruption of intestinal mucosal integrity because of
inflammation and apoptosis induced by inflammatory cytokines such as TNF-α (Tumor necrosis factor-alpha), IL-6 and ...
Protective effect of melatonin on cisplatin-induced liver injury in rats
(Cukurova Medical Journal, 2022)
Purpose: We aimed to evaluate the protective effect of melatonin (Mel) on experimental hepatatoxicity induced by cisplatin (Cis).
Materials and Methods: A total of 40 Wistar Albino rats were used. Control group (n = 10) ...
Chloroquine attenuates chronic hypoxia-induced testicular damage via suppressing endoplasmic reticulum stress and apoptosis in experimental rat model
(Wiley Online Library, 2022)
Chronic hypoxia negatively affects male fertility by causing pathological changes in male reproductive system. However, underlying mechanisms of this damage are unknown. Chloroquine (CLQ) is an anti-inflammatory agent that ...
The Ameliorative Effects of Caffeic Acid Phenethyl Ester in Cisplatin-Induced Nephrotoxicity: Assessment of the Oxidative Stress an Inflammation
(2021)
The aim of this study is to determine the potential therapeutic effects of CAPE in CP-induced nephrotoxicity in rats. Cisplatin (CP) is an antineoplastic chemotherapeutic used for treatment of many cancer types but its ...
Investigation of the Protective Effects of Caffeic Acid Phenethyl Ester against Cisplatin-induced Liver Damage in Rats
(2021)
Cisplatin (CP) is used as an effective chemotherapeutic drug in the treatment of various solid tumors. However, side effects such as hepatotoxicity limit the use of the drug. We investigated the protective effects of caffeic ...