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Kronik Hipoksiye Maruz Bırakılan Ratlardaki Mide Ghrelin Miktarı Üzerine Klorokuin’in Etkisi
(2019)
Giriş Amaç Yüksek irtifada yaşanan komplikasyonlardan biri olan Anoreksiya, çevresel
durumu sinyallerde enerji durumunu belirleyen ve iştahı kontrol eden hipoksinin neden olduğu
rahatsızlıklardan kaynaklanmaktadır. ...
Sisplatin’in Oluşturduğu Testis Hasarı Üzerine Kafeik Asit Fenetil Ester’in Koruyucu Etkisinin İncelenmesi
(Cell & Tissue Biology Research Turkish, Histology and Embryology Association, 2018)
Amaç: Testisler, erkek üreme hücrelerinin üretilmesi evresi olan spermatogenezin gerçekleştiği ve
testosteron başta olmak üzere erkek cinsiyet hormonlarının üretildiği yerlerdir. Antikanserojen bir
ilaç olan Sisplatin ...
Sisplatin’in Sıçanlarda Oluşturduğu Böbrek Hasarına Karşı Kafeik Asit Fenetil Ester’in Koruyucu Etkisinin İncelenmesi
(ZEUGMA II. ULUSLARARASI MULTİDİSİPLİNER ÇALIŞMALAR KONGRESİ, 2019)
Amaç: Sisplatin(SP), katı tümörlerin tedavisinde yaygın olarak kullanılan anti-kanserojen bir
ilaçtır. SP esas olarak böbrekler tarafından atılır ve ana yan etkilerinden biri nefrotoksisitedir
(1). Bu yüzden SP‟in doza ...
Effect of Chloroquine in Chronic Hypoxia-Induced Bowel Damage
(20. Ulusal Anatomi Kongresi, 2019)
Effect of chloroquine in chronic hypoxia-induced bowel damage
Researches on the protective effect of caffeic acid phenethyl ester on testicular 2 damage caused by cisplatin
(2020)
BACKGROUND/AIM:Cisplatin (CP), a chemotherapeutic drug, causes damage to spermatogenic serial cells, Sertoli cells and Leydig cells in rat testicles. We aimed to investigate the protective effect of caffeic acid phenethyl ...
Evaluation Of Epididymitis Tissue Of Cisplatin-Induced Rats
(SANAR, 2020)
As a chemotherapeutic agent, cisplatin is an antineoplastic agent used in the treatment of
various solid tumors such as lung, testicle and bladder cancer (Ezaki, Nishiumi, Azuma, &
Yoshida, 2017; Salem, Helmi, & Assaf, ...
Mitigative effects of chloroquine treatment against hypoxia-induced intestinal injury: a histological and immunohistochemical study
(Türk Hijyen ve Deneysel Biyoloji Dergisi, 2022)
Objective: Hypoxia has an important role in the disruption of intestinal mucosal integrity because of
inflammation and apoptosis induced by inflammatory cytokines such as TNF-α (Tumor necrosis factor-alpha), IL-6 and ...
Protective effect of melatonin on cisplatin-induced liver injury in rats
(Cukurova Medical Journal, 2022)
Purpose: We aimed to evaluate the protective effect of melatonin (Mel) on experimental hepatatoxicity induced by cisplatin (Cis).
Materials and Methods: A total of 40 Wistar Albino rats were used. Control group (n = 10) ...
Chloroquine attenuates chronic hypoxia-induced testicular damage via suppressing endoplasmic reticulum stress and apoptosis in experimental rat model
(Wiley Online Library, 2022)
Chronic hypoxia negatively affects male fertility by causing pathological changes in male reproductive system. However, underlying mechanisms of this damage are unknown. Chloroquine (CLQ) is an anti-inflammatory agent that ...
The Ameliorative Effects of Caffeic Acid Phenethyl Ester in Cisplatin-Induced Nephrotoxicity: Assessment of the Oxidative Stress an Inflammation
(2021)
The aim of this study is to determine the potential therapeutic effects of CAPE in CP-induced nephrotoxicity in rats. Cisplatin (CP) is an antineoplastic chemotherapeutic used for treatment of many cancer types but its ...
