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Mitigative effects of chloroquine treatment against hypoxia-induced intestinal injury: a histological and immunohistochemical study
(Türk Hijyen ve Deneysel Biyoloji Dergisi, 2022)
Objective: Hypoxia has an important role in the disruption of intestinal mucosal integrity because of
inflammation and apoptosis induced by inflammatory cytokines such as TNF-α (Tumor necrosis factor-alpha), IL-6 and ...
Chloroquine attenuates chronic hypoxia-induced testicular damage via suppressing endoplasmic reticulum stress and apoptosis in experimental rat model
(Wiley Online Library, 2022)
Chronic hypoxia negatively affects male fertility by causing pathological changes in male reproductive system. However, underlying mechanisms of this damage are unknown. Chloroquine (CLQ) is an anti-inflammatory agent that ...
Comparison of the Acute and Cumulative Dose Administrations in Doxorubicin-induced Hepatotoxicity via Evaluation of the Histopathological Changes and Inflammation in Rats
(Experimental and Applied Medical Science, 2020)
Doxorubicin (DOX) may lead to hepatotoxicity when administered chronically or in a high dose. The aim of this study is to determine dose–dependent effects of DOX in rat liver tissue. Thirty male Wistar albino rats were ...