Search
Now showing items 11-17 of 17
Protective effect of melatonin on cisplatin-induced liver injury in rats
(Cukurova Medical Journal, 2022)
Purpose: We aimed to evaluate the protective effect of melatonin (Mel) on experimental hepatatoxicity induced by cisplatin (Cis).
Materials and Methods: A total of 40 Wistar Albino rats were used. Control group (n = 10) ...
Chloroquine attenuates chronic hypoxia-induced testicular damage via suppressing endoplasmic reticulum stress and apoptosis in experimental rat model
(Wiley Online Library, 2022)
Chronic hypoxia negatively affects male fertility by causing pathological changes in male reproductive system. However, underlying mechanisms of this damage are unknown. Chloroquine (CLQ) is an anti-inflammatory agent that ...
The Ameliorative Effects of Caffeic Acid Phenethyl Ester in Cisplatin-Induced Nephrotoxicity: Assessment of the Oxidative Stress an Inflammation
(2021)
The aim of this study is to determine the potential therapeutic effects of CAPE in CP-induced nephrotoxicity in rats. Cisplatin (CP) is an antineoplastic chemotherapeutic used for treatment of many cancer types but its ...
Klorokuin endoplazmik retikulum stresini ve enflamasyonu inhibe ederek sıçanlarda adriamisin uyarılı kardiyotoksisiteyi engeller
(Türk Hijyen ve Deneysel Biyoloji Dergisi, 2020)
Amaç: Adriamisin (ADR) kanser türlerinde kullanılan kemoterapötik bir ilaç olarak bilinmektedir. ADR uyarılı kardiyomiyopati toksik özelliğinden dolayı ilacın kullanımını zorlaştırmaktadır. ADR uyarılı kardiyotoksisitede ...
Investigation of the Therapeutic Effects of Chloroquine in Adriamycin-Induced Hepatotoxicity
(Sciendo, 2021)
The aim of this study is to investigate the therapeutic effects of Chloroquine (CLQ) against Adriamycin (ADR) induced hepatotoxicity. ADR is a chemotherapeutic agent used in the treatment of many cancer types, but it causes ...
Comparison of the Acute and Cumulative Dose Administrations in Doxorubicin-induced Hepatotoxicity via Evaluation of the Histopathological Changes and Inflammation in Rats
(Experimental and Applied Medical Science, 2020)
Doxorubicin (DOX) may lead to hepatotoxicity when administered chronically or in a high dose. The aim of this study is to determine dose–dependent effects of DOX in rat liver tissue. Thirty male Wistar albino rats were ...
Histological evaluation of the effects of rapamycin and 3-methyladenine on cisplatin-induced epididymal injury in rats
(Cukurova Medical Journal, 2021)
Purpose: In this study, we aimed to determine the effects of autophagy inhibitor and activator on Cisplatin (Cis)-induced tissue damage.
Materials and Methods: A total of 24 male Wistar albino rats were divided into 4 ...