Crystal structure and Hirshfeld surface analysis of 10-hy­dr­oxy-2-(4-meth­­oxy­phen­yl)-3-oxo-2,3,3a,4,10,10a-hexa­hydro-1H-9-thia-2-aza­cyclo­penta­[b]fluorene-4-carb­­oxy­lic acid di­methyl sulfoxide-d6 monosolvate

Abstract

In the title compound, C22H19NO5S·C2D6OS, the central six-membered ring has a slightly distorted boat conformation, while the fused pyrrolidine ring adopts an envelope conformation. These conformations are stabilized by O—H⋯O hydrogen bonds between the main compound and solvent molecules. In addition, intramolecular C—H⋯O hydrogen bonds in the main molecule form two S(6) rings. Molecules are connected by pairs of intermolecular C—H⋯O hydrogen bonds, forming dimers with a R22(8) motif. These dimers form a three-dimensional network through O—H⋯O, O—H⋯S and C—H⋯O hydrogen bonds with each other directly and through solvent molecules. In addition, weak π–π stacking interactions [centroid-to-centroid distances = 3.9937 (10) and 3.9936 (10) Å, slippages of 2.034 and 1.681 Å] are observed. The intermolecular contacts were quantified using Hirshfeld surface analysis and two …