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  • Öğe
    Evaluation of the Results of Ganglion Impar Blockade in Patients with Chronic Coccydynia
    (2024) Gökoğlu, Abdulkerim; Yiğit, Hüseyin; Unur, Erdoğan
    Our study examined whether bupivacaine and steroid injections followed by Radiofrequency Thermocoagulation (RFT) improved symptoms among coccydynia patients. The Ganglion Impar Block (GIB) treatment of eight patients with coccydynia in our neurosurgery clinic was reviewed. A retrospective analysis of demographics, pain causes, X-ray results, types of invasive procedures, and Visual Analog Scale (VAS) and Oswestry Disability Index (ODI) scores was performed. VAS and ODI scores were recorded before the procedure, the first day after the procedure, and three months after the procedure. The study included five females (62.5%) and three males (27.5%). The mean age of the patients was 4 0.5 ± 10.6 years, and the mean BMI was 26.21 ± 4.2 kg/m². Two patients had idiopathic neuralgia, two had trauma -related neuralgia, two had post-herpetic neuralgia, and one patient had persistent pain following previous anorectal surgery and S2 perineural c ystrelated pain. There was a significant improvement in both VAS [2.5 (range: 1 -4)] and ODI scores [4 (range: 0-34)] on the first day after the procedure (p<0.001). These low scores were maintained at the third month [VAS: 1.5 (range: 1 -10) and ODI: 1 (range: 0-78)]. In only one patient, excision of the coccyx was planned due to inadequate pain relief. In patients with coccydynia, bupivacaine and steroid injections followed by RFT provide satisfactory long -term analgesia, as evidenced by decreased VAS and ODI scores.
  • Öğe
    Ophthalmic artery originating from anterior inferior cerebellar artery: a rare variation
    (Springer, 2024) Gökoğlu, Abdulkerim; Yiğit, Hüseyin; İnan, Enes; Öztürk, Burak; Dönmez, Halil; Selçuklu, Ahmet
    Purpose The variations of origin of ophthalmic artery are extremely rare. Here, we aimed to present a patient had a rare variation of the ophthalmic artery. Clinical presentation The patient had a history of Moyamoya disease. The imaging studies revealed ophthalmic artery origination from basillar artery. In addition, M1-segment fusiform aneurysm, vasculitis and, as a variation, middle meningeal artery originating from the ophthalmic artery were also detected. We presented this case report as it is the first case with ophthalmic artery originating from anterior inferior cerebellar artery. Conclusion In our case we reported, M1 segment fusiform aneurysm, vasculitis, and as a variation, middle meningeal artery originating from the ophthalmic artery and anterior inferior cerebellar artery as ophthalmic artery origin and hereby present it for inclusion into the literature. Ophthalmic artery anatomical abnormalities occupies so little place in existing literature when nominating rare variations. Ophtalmic artery originating from anterior inferior cerebellar artery firstly defined as an ophthalmic artery variation including its way-out branch structures.
  • Öğe
    Effect of cervical and lumbosacral spina bifida cystica on volumes of intracranial structures in children
    (Springer, 2023) Yiğit, Hüseyin; Güler, Hatice; Yılmaz, Halil; Gümüş, Ümmügülsüm Özgül; Karaman, Zehra Filiz; Güneş, Tamer
    Purpose Spina bifida is a major disorder that occurs when the membranes of the spinal cord and medulla fail to close during the embryonic period and affects the individual for the rest of life. Some physical, mental, and social difficulties can be observed in the lives of children with spina bifida after surgery. The aim of this study is to determine what kind of volumetric changes occur in the brain when spina bifida occurs in different regions of the cord. Methods The volume of intracranial structures of 14 children aged 1 to 9 years (7 cervical, 7 lumbosacral) with different levels of spina bifida compared with vol2Brain. Results Spina bifida occurring in the cervical region was found to cause a greater volumetric reduction in subcortical structures, cortex and gyrus than spina bifida occurring in the lumbosacral region. Conclusion We believe that our study will help clinicians involved in the management of this disorder.
  • Öğe
    Evaluating the brainstem in children with breathholding spells
    (KARE PUBL, 2023) Kaya Ozcora, Gul Demet; Kumandas, Sefer; Sagiroglu, Ayse; Acer, Niyazi; Doğanay, Selim; Yiğit, Hüseyin; Canpolat, Mehmet; Per, Hüseyin; Gümüş, Hakan
    OBJECTIVE: Breath-holding spells (BHSs) are a non-epileptic paroxysmal phenomenon characterized by frequent apnea episodes, loss of consciousness, and changes in skin tone and postural tone triggered by negative stimuli of childhood. The pathophysiology of the disease remains unclear; autonomic dysregulation caused by delayed myelination is believed to play a role. In this study, we aimed to evaluate the brainstems of children with BHS using diffusion tensor imaging (DTI) and investigate the etiology of this phenomenon. METHODS: The study group consisted of 16 children with a history of severe breath-holding episodes (accompanied by loss of consciousness and tonic contraction due to prolonged anoxic response) and 18 age-, gender-, and handedness-matched controls. All children underwent systemic, neurologic, and cardiologic evaluation, including complete blood count, blood bio-chemistry, serum iron and ferritin level, serum vitamin B12 level, electrocardiogram, and electroencephalograms. Magnetic resonance imaging was performed using a 1.5-Tesla Siemens Aera scanner (Siemens, Germany). RESULTS: Evaluation of brainstem (midbrain, pons, and medulla oblongata) volumes revealed no statistically significant differences between the BHS patient and control groups. In a voxel-wise analysis of DTI data, the BHS patient group had significantly lower fractional anisotropy (FA) values than the control group in the bilateral midbrain and medulla, right cortico-spinal tract, bilateral corpus callosum body and splenium, and left corpus callosum genu. In contrast, there were no significant differences in FA values in the pons, cerebellum, left corticospinal tract, and right corpus callosum genu. CONCLUSION: Based on our findings, we think that patients with BHS should be treated with an approach similar to other neurodevelopmental diseases and that this study may help elucidate the pathophysiology and establish the groundwork for future studies on its treatment.
  • Öğe
    Effects of pseudoephedrine on rat fetal bone development: evaluation by three different methods
    (SPRINGER, 2023) Yiğit, Hüseyin; Balcıoğlu, Esra; Uçar, İlyas; Değermenci, Muhammet; Önder, Gözde Özge; Ceylan, Tayfun; Unur, Erdoğan
    Pseudoephedrine (PSE) is an agent that is contained in common cold medications. The agent, which is used to treat cold and cough, is the fourth most prescribed drug group in some countries. During pregnancy, expectant mothers use PSE for colds and other reasons. One out of every four expectant mothers use PSE alone or in combination with other medicines for various reasons. This study was aimed to investigate effects of PSE on long bones development in rat during fetal growth. Pregnant rats were divided into five groups: control and four experimental groups (25 mg/kg, 50 mg/kg, 100 mg/kg, 200 mg/kg PSE). Between 1 and 20 days of pregnancy, PSE was given to them by gavage. Weights and heights of fetuses isolated by cesarean on the 21st day were measured. Ossification of femur and humerus was examined by three different methods mentioned earlier. Depending on the dose increase, all morphometric data, ossification rate and bone length of the fetuses were decreased. Besides, it was determined that the amount of Calcium in the bone tissue decreased in the analyzes made with SEM–EDX Analysis. The data obtained from this study reveal that the use of PSE during pregnancy disrupts the existing balance in the bone and negatively affects ossification due to the dose increase. In conclusion, we present descriptive and novel data on the effects of PSE use during pregnancy on the bone development of rat fetal long bones.