Evaluation of The Interaction Between Alternative Endodontic Irrigation Solutions

Statement of the problem: For successful endodontic treatment, mecha-nical cleaning and chemical irrigation can be used together. Since there is not yet a single solution sufficient for both root canal cleaning alone, combined use of irrigants is recommended for the synergistic effect. Polyhexanide (PHMB), boric acid, phytic acid, peracetic acid, and hypochlorous acid are relatively new alternative endodontic irrigation solutions and there are no studies in the lite-rature on the combined use of alternative solutions. Objective: This study aimed to evaluate the interactions that would re-sult from applying PHMB as a substitute for CHX following alternative inter-mediate irrigation solutions that might be utili-zed with NaOCl. Materials & Methods: Eight microtubes were used for this study. 0.5ml of 5%NaOCl was placed in each microtube first, the microtubes were divided into two groups as the final product CHX and Polyhexanide, and the two gro-ups were divided into four groups with different irrigants in themselves. The study was conducted at room temperature and the images of the mixtures were photographed at 1 min, 10 min, 20 min, 30 min, and 1 hour. Groups; G1: NaOCl+ 1%Phytic acid +0.1%Polyhexanide, G2: NaOCl+ 0.02%Hypochlorous acid +0.1%Polyhexanide, G3: NaOCl+ 2% Peracetic acid +0.1%Polyhexanide, G4: Na-OCl+ 5% Boric acid +0.1%Polyhexanide, G5: NaOCl+ Phytic acid+ 2%CHX, G6: NaOCl+ 0.02%Hypochlorous acid +2%CHX, G7: NaOCl+ 2% Peracetic acid+2%CHX, G8: NaOCl+ 5% Boric acid + 2%CHX. Results: White or brown precipitates occurred as soon as the solutions were applied to all of the CHX groups; milky-white precipitate was only seen in the Polyhexanide group's Phytic acid-added group. After 5 minutes, air bubbles were seen in the Polyhexanide group that had Peracetic acid added, whereas the CHX group had an increase in brown precipitates. Conclusions: Considering the current research conditions, In clinical practice, the administration of Polyhexanite as the last irrigant and the combi-nation of NaOCl with boric acid or hypochlorous acid can be advised.