Alterations in the Antimicrobial Resistance Profile of Acinetobacter baumannii Strains Isolated from Intensive Care Unit Patients: Five-Year Follow-up in Cappadocia

Basit Öğe Kaydı
dc.authorid0000-0001-7726-0968
dc.contributor.authorAkman, Nazife
dc.contributor.authorÖzmen, Pelin
dc.contributor.authorTürk, Mustafa
dc.date.accessioned2025-02-04T08:41:24Z
dc.date.available2025-02-04T08:41:24Z
dc.date.issued2024en_US
dc.departmentKapadokya Üniversitesi, Kapadokya Meslek Yüksekokulu, Patoloji Laboratuvar Teknikleri Bölümü
dc.description.abstractBackground: This study aims to determine alterations in the antibiotic resistance status of Acinetobacter baumannii strains isolated from lower respiratory tract samples of patients in intensive care units over the years. Methods: In this comprehensive study, A. baumannii strains isolated from aspirate and sputum samples of patients hospitalized in intensive care units of a second-stage state hospital between January 2018 and December 2022 were meticulously and retrospectively investigated and analyzed for antimicrobial resistance. Results: The rate of aspirate and sputum samples in the study was 18.1% (754/4151); The positivity rate of cultures was 51.7% (390/754); The rate of those associated with A. baumannii was found to be 65.6% (256/390).. 90.2% of the isolates were isolated from the general intensive care unit (231/256). The rates of A. baumannii isolated from aspirate and sputum samples were 67.4% (213/316) and 58.1% (43/74), respectively. The carbapenem resistance rate in A. baumannii isolates grown in aspirate samples was 96.5%, fluoroquinolone resistance was 91.7%; The carbapenem resistance rate in sputum samples was 96.1% and fluoroquinolone resistance was 90.9%. The most effective antibiotics against A. baumannii strains isolated from both aspirate and sputum samples were colistin 100% (n=256), TMP/SXT 55.8% (143/256), tigecycline 50.3% (129/256), respectively. Conclusion: Our study reveals a concerning trend-a high frequency of multidrug-resistant A. baumannii isolates are being identified in the Central Anatolia region of our country. This high prevalence, which is a cause for immediate concern, underscores the urgent and immediate need for robust infection control measures to curb the spread of A. baumannii in hospitals.
dc.identifier.citationAkman N, Özmen P, Türk M. Alterations in the Antimicrobial Resistance Profile of Acinetobacter baumannii Strains Isolated from Intensive Care Unit Patients: Five-Year Follow-up in Cappadocia Microb.esInfect Chemother. 2024; 4: e2235
dc.identifier.issue4en_US
dc.identifier.urihttps://revistas.unheval.edu.pe/index.php/mic/article/view/2235
dc.identifier.urihttps://doi.org/10.54034/mic.e2235
dc.identifier.urihttps://hdl.handle.net/20.500.12695/3206
dc.identifier.volume2024en_US
dc.language.isoen
dc.publisherUniversidad Nacional Hermilio Valdizán of Huánuco.
dc.relation.ispartofMicrobes, Infection and Chemotherapy
dc.relation.publicationcategoryMakale - Uluslararası - Editör Denetimli Dergi
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rights.urihttps://creativecommons.org/licenses/by-nd/4.0/*
dc.subjectAcinetobacter baumannii
dc.subjectcarbapenem resistance
dc.subjectintensive care unit
dc.subjectlower respiratory tract
dc.titleAlterations in the Antimicrobial Resistance Profile of Acinetobacter baumannii Strains Isolated from Intensive Care Unit Patients: Five-Year Follow-up in Cappadocia
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
Yayın 2- Microbes-infection-chemotherapy dergisi.pdf
Boyut:
885.98 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Makale / Article
İndir
Lisans paketi
Listeleniyor 1 - 1 / 1
[ X ]
İsim:
license.txt
Boyut:
1.44 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

PLT - Makale Koleksiyonu