Browsing by Author "Kaymak, Emin"
Now showing items 21-29 of 29
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Mitigative effects of chloroquine treatment against hypoxia-induced intestinal injury: a histological and immunohistochemical study
Akin, Ali Tuğrul; Kaymak, Emin; Öztürk, Emel; Ceylan, Tayfun; Yalçın, Betül; Başaran, Kemal Erdem; Karabulut, Derya; Doğanyiğit, Züleyha; Özdamar, Saim; Yakan, Birkan (Türk Hijyen ve Deneysel Biyoloji Dergisi, 2022)Objective: Hypoxia has an important role in the disruption of intestinal mucosal integrity because of inflammation and apoptosis induced by inflammatory cytokines such as TNF-α (Tumor necrosis factor-alpha), IL-6 and ... -
Protective effect of melatonin on cisplatin induced acute kidney injury: Role of regulation of heat shock proteins expressions
Akin, Ali Tuğrul; Ünsal, Murat; Ceylan, Tayfun; Kaymak, Emin; Öztürk, Emel; Kuloğlu, Nurhan; Karabulut, Derya; Yakan, Birkan (Indian Journal of Experimental Biology, 2023)Chemotherapy is one of the major treatment approaches for cancer, and these agents are known to cause severe side effects, including damaging vital organs. Cisplatin (CP) is a commonly used chemotherapeutic agent in the ... -
Protective effect of melatonin on cisplatin-induced liver injury in rats
Kaymak, Emin; Ünsal, Murat; Akin, Ali Tuğrul; Öztürk, Emel; Ceylan, Tayfun; Kuloğlu, Nurhan; Karabulut, Derya; Yakan, Birkan (Cukurova Medical Journal, 2022)Purpose: We aimed to evaluate the protective effect of melatonin (Mel) on experimental hepatatoxicity induced by cisplatin (Cis). Materials and Methods: A total of 40 Wistar Albino rats were used. Control group (n = 10) ... -
Research on Endoplasmic Reticulum Stress-mediated Protective Effect of Melatonin against Cardiotoxicity Following Cisplatin Treatment
Ceylan, Tayfun; Ünsal, Murat; Kaymak, Emin; Akin, Ali Tuğrul; Kuloğlu, Nurhan; Karabulut, Derya; Yakan, Birkan (Medical Journal of Bakirkoy, 2024)Objective: Cisplatin (CP) is a chemotherapeutic drug that causes cardiotoxicity. Melatonin (MEL) is secreted by the pineal gland throughout the night. This study aimed to investigate the protective effect of MEL against ... -
Researches on the protective effect of caffeic acid phenethyl ester on testicular 2 damage caused by cisplatin
BACKGROUND/AIM:Cisplatin (CP), a chemotherapeutic drug, causes damage to spermatogenic serial cells, Sertoli cells and Leydig cells in rat testicles. We aimed to investigate the protective effect of caffeic acid phenethyl ... -
Sisplatin’in Oluşturduğu Testis Hasarı Üzerine Kafeik Asit Fenetil Ester’in Koruyucu Etkisinin İncelenmesi
Ceylan, Tayfun; Kaymak, Emin; Yalçın, Betül; Cantürk Tan, Fazile; Yakan, Birkan (Cell & Tissue Biology Research Turkish, Histology and Embryology Association, 2018)Amaç: Testisler, erkek üreme hücrelerinin üretilmesi evresi olan spermatogenezin gerçekleştiği ve testosteron başta olmak üzere erkek cinsiyet hormonlarının üretildiği yerlerdir. Antikanserojen bir ilaç olan Sisplatin ... -
Sisplatin’in Sıçanlarda Oluşturduğu Böbrek Hasarına Karşı Kafeik Asit Fenetil Ester’in Koruyucu Etkisinin İncelenmesi
Ceylan, Tayfun; Kaymak, Emin; Yakan, Birkan (ZEUGMA II. ULUSLARARASI MULTİDİSİPLİNER ÇALIŞMALAR KONGRESİ, 2019)Amaç: Sisplatin(SP), katı tümörlerin tedavisinde yaygın olarak kullanılan anti-kanserojen bir ilaçtır. SP esas olarak böbrekler tarafından atılır ve ana yan etkilerinden biri nefrotoksisitedir (1). Bu yüzden SP‟in doza ... -
Thymoquinone reduces methotrexate-induced heart damage: a histopathological study in rats
Yıldırım, Ayşegül Burçin; Kaymak, Emin; Ceylan, Tayfun; Akin, Ali Tuğrul; Kuloğlu, Nurhan; Sayan, Meryem; Değer, Necla; Önal, Esra; Karabulut, Derya (Cukurova Medical Journal, 2023)Purpose: The study aimed to evaluate the effect of thymoquinone on cardiac tissue in MTX-induced cardiac toxicity in rats with various parameters. Materials and Methods: Group I (n=8) was administered intraperitoneal ... -
Unveiling the Protective Potential of Crocin in Septic Acute Liver Injury via Assessment of TLR4/HGM1/NF‐κB Signaling Pathway, Oxidative Stress and Heat Shock Response
Akin, Ali Tuğrul; Kaymak, Emin; Ceylan, Tayfun; Kuloğlu, Nurhan; Karabulut, Derya; Toluk, Ayşe (Cell Biochemistry and Function, 2025)Sepsis, defined as a systemic inflammatory response, is one of the conditions with the highest mortality rates. Crosin (CRO) is one of the active ingredients in saffron and known for its various pharmacological effects. ...
