Browsing by Author "Önal, Esra"

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Effect of thymoquinone on NRF2/NF-kB/MAPK pathway in methotrexate-induced rat testis injury

Kaymak, Emin; Ceylan, Tayfun; Akin, Ali Tuğrul; Kuloğlu, Nurhan; Sayan, Meryem; Değer, Necla; Önal, Esra; Yıldırım, Ayşegül Burçin; Karabulut, Derya (Iranian Journal of Basic Medical Sciences, 2024)

Objective(s): In this study, we aimed to investigate the protective effect of Thymoquinone (THQ) against testicular damage caused by Methotrexate (MTX). Materials and Methods: This study consists of 5 groups: Control, ...
Thymoquinone reduces methotrexate-induced heart damage: a histopathological study in rats

Yıldırım, Ayşegül Burçin; Kaymak, Emin; Ceylan, Tayfun; Akin, Ali Tuğrul; Kuloğlu, Nurhan; Sayan, Meryem; Değer, Necla; Önal, Esra; Karabulut, Derya (Cukurova Medical Journal, 2023)

Purpose: The study aimed to evaluate the effect of thymoquinone on cardiac tissue in MTX-induced cardiac toxicity in rats with various parameters. Materials and Methods: Group I (n=8) was administered intraperitoneal ...