Browsing by Author "Özdamar, Saim"
Now showing items 1-6 of 6
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Chloroquine attenuates chronic hypoxia-induced testicular damage via suppressing endoplasmic reticulum stress and apoptosis in experimental rat model
Akin, Ali Tuğrul; Kaymak, Emin; Ceylan, Tayfun; Öztürk, Emel; Başaran, Kemal Erdem; Karabulut, Derya; Özdamar, Saim; Yakan, Birkan (Wiley Online Library, 2022)Chronic hypoxia negatively affects male fertility by causing pathological changes in male reproductive system. However, underlying mechanisms of this damage are unknown. Chloroquine (CLQ) is an anti-inflammatory agent that ... -
Comparison of the Acute and Cumulative Dose Administrations in Doxorubicin-induced Hepatotoxicity via Evaluation of the Histopathological Changes and Inflammation in Rats
Akin, Ali Tuğrul; Kaymak, Emin; Karabulut, Derya; Doğanyiğit, Züleyha; Ceylan, Tayfun; Toluk, Ayşe; Özdamar, Saim (Experimental and Applied Medical Science, 2020)Doxorubicin (DOX) may lead to hepatotoxicity when administered chronically or in a high dose. The aim of this study is to determine dose–dependent effects of DOX in rat liver tissue. Thirty male Wistar albino rats were ... -
The Dose-Dependent Effects Of Doxorubicin In Ratliver Tissue
Akin, Ali Tuğrul; Kaymak, Emin; Karabulut, Derya; Doğanyiğit, Züleyha; Ceylan, Tayfun; Toluk, Ayşe; Özdamar, Saim (1st International Ahi Evran Medical and Health Science Congress (IAMHC), 2019)Introduction: Doxorubicin (DOX) is an anthracycline antibiotic used as an anticancer agent and is a widely used chemotherapeutic for many cancer types such as sarcoma, acute lymphoblastic leukaemia and as well as breast ... -
Effect of Chloroquine in Chronic Hypoxia-Induced Bowel Damage
Kaymak, Emin; Akin, Ali Tuğrul; Yalçın, Betül; Öztürk, Emel; Ceylan, Tayfun; Başaran, Kemal Erdem; Karabulut, Derya; Doğanyiğit, Züleyha; Özdamar, Saim; Yakan, Birkan (20. Ulusal Anatomi Kongresi, 2019)Effect of chloroquine in chronic hypoxia-induced bowel damage -
Kronik Hipoksiye Maruz Bırakılan Ratlardaki Mide Ghrelin Miktarı Üzerine Klorokuin’in Etkisi
Kaymak, Emin; Akin, Ali Tuğrul; Öztürk, Emel; Yalçın, Betül; Ceylan, Tayfun; Başaran, Kemal Erdem; Doğanyiğit, Züleyha; Karabulut, Derya; Özdamar, Saim; Yakan, Birkan (2019)Giriş Amaç Yüksek irtifada yaşanan komplikasyonlardan biri olan Anoreksiya, çevresel durumu sinyallerde enerji durumunu belirleyen ve iştahı kontrol eden hipoksinin neden olduğu rahatsızlıklardan kaynaklanmaktadır. ... -
Mitigative effects of chloroquine treatment against hypoxia-induced intestinal injury: a histological and immunohistochemical study
Akin, Ali Tuğrul; Kaymak, Emin; Öztürk, Emel; Ceylan, Tayfun; Yalçın, Betül; Başaran, Kemal Erdem; Karabulut, Derya; Doğanyiğit, Züleyha; Özdamar, Saim; Yakan, Birkan (Türk Hijyen ve Deneysel Biyoloji Dergisi, 2022)Objective: Hypoxia has an important role in the disruption of intestinal mucosal integrity because of inflammation and apoptosis induced by inflammatory cytokines such as TNF-α (Tumor necrosis factor-alpha), IL-6 and ...
