Browsing by Author "Zengin Kurt, Belma"

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In vitro α-glucosidase, docking and density functional theory studies on novel azide metal complexes

Avcı, Davut; Özge, Özgen; Sönmez, Fatih; Tamer, Ömer; Başoğlu, Adil; Atalay, Yusuf; Zengin Kurt, Belma (Future Medicinal Chemistry, 2024)

The goal of this study is to synthesize new metal complexes containing N-methyl-1-(pyridin-2-yl)methanimine and azide ligands as α-glucosidase inhibitors for Type 2 diabetes. Materials & methods: The target complexes (12–16) ...
Synthesis, DFT calculations, α-glucosidase inhibitor activity, and docking studies on Schiff base metal complexes containing isothiocyanate

Özge, Özgen; Avcı, Davut; Sönmez, Fatih; Tamer, Ömer; Dege, Necmi; Başoğlu, Adil; Atalay, Yusuf; Zengin Kurt, Belma (WILEY, 2023)

Diabetes is one of the fastest growing global health crises of the 21st century. One of the current therapeutic approaches used in the treatment of diabetes involves the suppression of carbohydrate hydrolyzing enzymes ...