Antimicrobial peptides (AMPs): A promising class of antimicrobial compounds

dc.authorid0000-0002-8724-0466
dc.contributor.authorErdem Büyükkiraz, Mine
dc.contributor.authorKesmen, Zülal
dc.date.accessioned2022-02-16T06:41:15Z
dc.date.available2022-02-16T06:41:15Z
dc.date.issued2021en_US
dc.departmentKapadokya Üniversitesi, Sağlık Bilimleri Yüksekokulu, Beslenme ve Diyetetik Bölümü
dc.descriptionTARAMAWOS
dc.descriptionTARAMAPUBMED
dc.descriptionTARAMASCOPUS
dc.description.abstractAntimicrobial peptides (AMPs) are compounds, which have inhibitory activity against microorganisms. In the last decades, AMPs have become powerful alternative agents that have met the need for novel anti-infectives to overcome increasing antibiotic resistance problems. Moreover, recent epidemics and pandemics are increasing the popularity of AMPs, due to the urgent necessity for effective antimicrobial agents in combating the new emergence of microbial diseases. AMPs inhibit a wide range of microorganisms through diverse and special mechanisms by targeting mainly cell membranes or specific intracellular components. In addition to extraction from natural sources, AMPs are produced in various hosts using recombinant methods. More recently, the synthetic analogues of AMPs, designed with some modifications, are predicted to overcome the limitations of stability, toxicity and activity associated with natural AMPs. AMPs have potential applications as antimicrobial agents in food, agriculture, environment, animal husbandry and pharmaceutical industries. In this review, we have provided an overview of the structure, classification and mechanism of action of AMPs, as well as discussed opportunities for their current and potential applications.
dc.identifier.citationErdem Büyükkiraz, M., & Kesmen, Z. Antimicrobial peptides (AMPs): A promising class of antimicrobial compounds. J Appl Microbiol. 2021;00:1–24. doi: 10.1111/jam.15314
dc.identifier.doi10.1111/jam.15314
dc.identifier.endpage24en_US
dc.identifier.issue00en_US
dc.identifier.scopusqualityN/A
dc.identifier.startpage1en_US
dc.identifier.urihttps://doi.org/10.1111/jam.15314
dc.identifier.urihttps://hdl.handle.net/20.500.12695/1489
dc.identifier.wosWOS:000706785500001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Sceince
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorErdem Büyükkiraz, Mine
dc.language.isoen
dc.publisherJournal of Applied Microbiology
dc.relation.ispartofJournal of Applied Microbiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Başka Kurum Yazarı
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectantibacterial
dc.subjectantimicrobial peptides
dc.subjectantiviral
dc.subjectapplications of AMPs
dc.subjectmechanism of action
dc.subjectorigins of AMPs
dc.titleAntimicrobial peptides (AMPs): A promising class of antimicrobial compounds
dc.typeArticle

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